重庆医学Issue(1)：63-65,3.DOI:10.3969/j.issn.1671-8348.2015.01.022
叉头框蛋白Q1在非小细胞肺癌的表达及其与预后关系
Expression and relationship between forkhead box Q1 and prognosis in NSCLC
王斌 1张逊 2耿华 3徐美林 3周海英4
作者信息
- 1. 天津医科大学第四中心临床学院胸外科 300140
- 2. 天津胸科医院胸外科 300051
- 3. 天津胸科医院病理科 300051
- 4. 唐山工人医院胸外科，河北唐山063000
- 折叠
摘要
Abstract
Objective To study the expression of forkhead box Q1(FOXQ1)in non‐small cell lung cancer(NSCLC) ,then investi‐gate clinical pathological characteristics of NSCLC and its prognosis in patients .Methods The expression of FOXQ1 in 84 cases of NSCLC(selected from June 2007 to December 2008 )was detected by immunohistochemistry(SP) .The correlations of the expres‐sion of FOXQ1 with clinic pathological features and survival time of the NSCLC patients were analyzed .Results The positive ex‐pression rate of FOXQ1 was 91 .7% (77/84) ,closely correlated with patients`histological type and TNM stage(P<0 .05) .The Cox multivariate analysis demonstrated that histological type ,TNM stage and FOXQ1expression were independent factors of NSCLC (P<0 .05) .Conclusion The expression of FOXQ1 may be highly expressed in NSCLC and negatively correlated with prognosis .关键词
肺肿瘤/癌,非小细胞肺/预后/叉头框蛋白Q1Key words
lung neoplasms/carcinoma ,non-small cell lung/prognosis/foxhead box Q1分类
医药卫生引用本文复制引用
王斌,张逊,耿华,徐美林,周海英..叉头框蛋白Q1在非小细胞肺癌的表达及其与预后关系[J].重庆医学,2015,(1):63-65,3.
