重庆医学Issue(9)：1211-1214,4.DOI:10.3969/j.issn.1671-8348.2015.09.019
乳腺浸润性微乳头状癌临床病理学特征及预后分析
The clinicopathological characteristics and prognosis in invasive micropapillary carcinoma of the breast
玛依努尔・阿里甫 1朱丽萍 1吐鲁洪・沙列尔 1王斌 1杨亮 1吴涛 1赵倩 1迪力夏提・金斯汗1
作者信息
- 1. 新疆医科大学附属肿瘤医院乳腺外科，乌鲁木齐830000
- 折叠
摘要
Abstract
Objective This study aims to compare the differences of the clinical data between invasive micropapillary carcino-ma(IMPC) and invasive ductal carcinoma (IDC) ,and explore the clinicopathologic and immunohistochemical characteristics ,molec-ular subtypes and survival condition of invasive micropapillary carcinoma of the breast .Methods Forty-two IMPC from January 2008 to October 2013 compared with 136 patients identified as IDC in this hospital during the same period .The clinicopathologic characteristics and molecular subtypes were analyzed .Results IMPC significantly differed from the IDC patients in terms of fertili-ty status ,history of benign breast ,lymph node metastasis ,lymphatic invasion ,extranodal extention ,mammilla invasion ,TNM stage , ER expression(P<0 .05) .Meanwhile no statistically significant found in the differential expression of nationality ,menopausal sta-tus ,tumor family history ,clinical presentation ,tumor size ,histological grade ,PR ,HER2 ,Ki67 ,molecular typing ,local recurrence , distant metastasis ,disease-free survival and overall survival .Univariate analysis showed that the patients who lymph node metasta-sis ,ER-negative ,TNM stage Ⅲ had the poor prognosis at 2-year disease-free survival .Conclusion The women who have the histo-ry of benign breast disease and infertility may have higher risk in the incidence of IM PC .Its 2 year disease-free survival may related with lymph node metastasis ,ER and pathological staging .关键词
乳腺浸润性微乳头状癌/临床病理学/免疫组织化学染色/分子分型/预后分析Key words
invasive/infiltrativec micropapillary carcinoma/clinicopathologic immunohistochemical characteristics/molecular subtype/prognosis分类
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玛依努尔・阿里甫,朱丽萍,吐鲁洪・沙列尔,王斌,杨亮,吴涛,赵倩,迪力夏提・金斯汗..乳腺浸润性微乳头状癌临床病理学特征及预后分析[J].重庆医学,2015,(9):1211-1214,4.
