重庆医学Issue(14)：1931-1933,3.DOI:10.3969/j.issn.1671-8348.2015.14.022
2003～2011年某院呼吸科病原菌的分布及耐药性分析
Analysis on distribution and drug resistance of pathogens in respiratory department from 2003 to 2011
摘要
Abstract
Objective To analyze the distribution and drug resistance situation of pathogens in the respiratory department during the recent 9 years to provide the basis for rational use of antibacterial drugs in clinic .Methods All pathogens isolated from the respiratory depeartment from January 2003 to December 2011 and the drug susceptibility test results were retrospectively and statistically analyzed .Results A total of 5 714 strains of pathogenic bacteria were isolated ,which mainly distributed in the sputum (90 .1% ) ,excrement (4 .2% ) and urine (3 .6% );among them ,2 943 strains (51 .5% ) were Gram‐negative bacteria ,596 strains (10 .4% ) were Gram‐positive bacteria and 2 175 strains (38 .1% ) were fungi .The top six of isolated bacteria were Candida albi‐cans ,Pseudomonas aeruginosa ,Acinetobacter baumannii ,Klebsiella pneumoniae ,Candida tropicalis and Escherichia coli .The isola‐tion rates of A .baumannii and C .albicans were increased year by year ,while the isolation rate of E .coli was decreased .A .baumannii and P .aeruginosa had a high resistant to all antibacterial drugs ,whereas the resistant rate of A .baumannii was increased year by year and that of P .aeruginosa showed some fluctuation .K .pneumoniae had a high susceptibility to imipenem and meropenem ,and the sensitivity to other antimicrobial agents had a gradually increasing tendency .The sensitive rate of C .albicans to amphotericin B was almost 100% ,and they had a high susceptible to other antifungal agents .Conclusion Drug resistance of the pathogens is com‐mon in the respiratory department .It is of importance to emphasize the pathologic examination ,carry out the surveillance of drug re‐sistance of pathogenic bacteria ,and use the antibacterial drugs rationally in clinical anti‐infective therapy .关键词
耐药性/病原菌/抗菌药物/呼吸科Key words
drug resistance/pathogen/antimicrobial agent/respiratory department分类
医药卫生引用本文复制引用
孙凤军,戴晓天,冯伟,罗光明,熊玮..2003～2011年某院呼吸科病原菌的分布及耐药性分析[J].重庆医学,2015,(14):1931-1933,3.基金项目
国家科技重大专项基金资助项目（2011ZX09302-033-01）。 （）
