重庆医学Issue(15)：2048-2050,3.DOI:10.3969/j.issn.1671-8348.2015.15.011
硬膜外复合皮下多模式镇痛用于开胸食管癌手术患者的临床研究
Clinical research on application of epidural and subcutaneous multimodal analgesia in thoracotomy esophageal cancer operation
摘要
Abstract
Objective To study the analgesia effect and adverse reactions of epidural and subcutaneous multimodal analgesia in thoracotomy esophageal cancer resection operation .Methods Forty patients undergoing elective esophageal cancer resection op‐eration were randomly divided into the epidural and subcutaneous analgesia group (group A) and the subcutaneous analgesia group (group B) ,20 cases in each group .The group A adopted 0 .15% ropivacaine and 0 .00002% sufentanil by continuous pumping infu‐sion before and during operation for continuous analgesia ,then intravenous tramadol was given before closing chest ,tramadol and sufentanil subcutaneous patients self‐control analgesia (PCA)were used after operation for analgesia .The group B was given intra‐venous tramadol before closing chest ,then tramadol and sufentanil patient subcutaneous controlled analgesia after operation were used for analgesia .The scores of the visual analogue scale(VAS) ,comfort scale ,sedative scores ,dose of analgesics ,pressing fre‐quency and pressing frequency ratio of PCA ,vital signs and adverse reactions were assessed at different time periods .Results The VAS scores and pressing frequency of PCA at rest and movement in the group A were remarkably decreased compared with the group B ,while the comfort status score and pressing frequency ratio of PCA were obviously increased ,the differences were statisti‐cally significant(P<0 .05);the occurrence rates of adverse reactions such as the vital signs ,sedative scores ,nausea ,vomitting ,skin itch ,chest distress after operation had no statistically significant differences between the two groups .Conclusion Epidural and sub‐cutaneous multimodal analgesia is a better multimodal analgesia scheme in thoracotomy esophageal cancer resection operation .关键词
食管肿瘤/镇痛 ,硬膜外/罗哌卡因/曲马多Key words
esophageal cancer/analgesia ,epidural/ropivacaine/tramadol分类
医药卫生引用本文复制引用
刘梦虓,熊章荣,牟林,魏闯,唐延先..硬膜外复合皮下多模式镇痛用于开胸食管癌手术患者的临床研究[J].重庆医学,2015,(15):2048-2050,3.基金项目
重庆市卫生局医学科学技术基金资助项目（2011-2-361）。 （）
