重庆医学Issue(16):2164-2166,3.DOI:10.3969/j.issn.1671-8348.2015.16.002
不明原因反复自然流产妇女蜕膜中树突状细胞亚群的变化
The changes of the subsets of dendritie cells in patients with unexplained early spontaneous abortion
摘要
Abstract
Objective To explore the changes of the subsets of dendritie cells(DC) in normal pregnant women and patients with unexplained early spontaneous abortion .Methods Twenty normal pregnant women and 21 unexplained early spontaneous a‐bortion patients were included in this study .The DC were stained with monoclonal antibodies and estimated by the flow cytometric method .Comparson of the numbers and subsets of DC in the decidua were performed between the two groups .Results The level of DC and MDC ,MDC/PDC ratio in the decidua of spontaneous abortion patients were higher than the normal pregnant women (P<0 .05) .Conclusion The percentage of DC and myeloid DC and the MDC/PDC ratio in the unexplained early spontaneous abortion patients is significantly higher than that in the normal pregnant women .It may contribute to the spontaneous abortion .关键词
树突细胞/流产,自然/蜕膜/流式细胞术Key words
dendritic cell/abortion ,spontaneous/decidua/flow cytometry分类
医药卫生引用本文复制引用
张艳霞,高天旸,李梅清,周长华,陈哲,全燕,赵雪峰,李锐..不明原因反复自然流产妇女蜕膜中树突状细胞亚群的变化[J].重庆医学,2015,(16):2164-2166,3.基金项目
广东省社会发展领域科技计划基金项目(20120318080)。 ()