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液相微萃取HPLC测定消癌平口服液中绿原酸含量

张敏 李海茹

吉林医药学院学报Issue(1):15-17,3.
吉林医药学院学报Issue(1):15-17,3.

液相微萃取HPLC测定消癌平口服液中绿原酸含量

The determination of chlorogenic acid content in Xiao'aiping oral liquid by liquid phase microextraction HPLC

张敏 1李海茹2

作者信息

  • 1. 空军太原干休所卫生所,山西 太原 030006
  • 2. 山西省肿瘤医院药学部,山西 太原030013
  • 折叠

摘要

Abstract

Objective To study the quantitative method for chlorogenic acid in Xiao'aiping oral liquid .Methods High performance liquid chromatography ( HPLC) were employed.Chromatographic column was Eclipse XDB-C18 column (150 mm ×4.6 mm ×5μm),mobile phase was acetonitrile-0.4%phosphoric acid solution (8∶92);and de-tection wavelength was 327 nm.Results The linear range of chlorogenic acid covered from 1.60μg to 160μg (r=0.999 5,n=5),and the average sample recovery rate was 99.3%,RSD=2.4%.Conclusion This method is sim-ple,sensitive,accurate,and can be for Xiao'aiping oral liquid quality control .

关键词

消癌平口服液/绿原酸/液相微萃取

Key words

Xiao'aiping oral liquid/chlorogenic acid/the liquid phase microextraction

分类

医药卫生

引用本文复制引用

张敏,李海茹..液相微萃取HPLC测定消癌平口服液中绿原酸含量[J].吉林医药学院学报,2015,(1):15-17,3.

吉林医药学院学报

1673-2995

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