动物医学进展Issue(5)：81-84,4.
盐酸沃尼妙林软膏剂的制备及抗金黄色葡萄球菌效果研究
Study on Prepartion and Antibacterial Effects of Valnemulin Hydrochloride Ointments
摘要
Abstract
To study transdermal drug release ration of valnemulin hydrochloride ointments invitro and the resistant-ce to S.aureus infection,two kinds of valnemulin hydrochloride ointments,W/O and O/W,were prepared by u-sing emulsification method,the percutaneous permeability ration was determined by HPLC.Two types of valne-mulin hydrochloride ointments showed good stability;the percutaneous penetration rates of W/O and O/W oint-ments were 30%±0.42% and 18.45%±0.69% after 10 hours,respectively.Two types of valnemulin hydro-chloride ointments also showed good treatment results for subcutaneous infections caused by S.aureus in mice,but the W/O ointment shown better result than the O/W formulation.关键词
盐酸沃尼妙林软膏剂/透皮释药率/金黄色葡萄球菌/感染Key words
Valnemulin hydrochloride ointment/transdermal drug delivery rate/S.aureus/infection分类
农业科技引用本文复制引用
何江梅,苏婷婷,余红艳,黄兴亮,陈章宝..盐酸沃尼妙林软膏剂的制备及抗金黄色葡萄球菌效果研究[J].动物医学进展,2014,(5):81-84,4.基金项目
重庆市科委科技攻关项目 （）
