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流感病毒感染雪貂的标准化操作程序建立

张涛 徐娟 杨凤梅 秦晓峰 程根宏 和占龙

动物医学进展Issue(10):25-29,5.
动物医学进展Issue(10):25-29,5.

流感病毒感染雪貂的标准化操作程序建立

Standard Operation Procedures of Influenza Virus Infection Model in Ferret

张涛 1徐娟 1杨凤梅 2秦晓峰 1程根宏 1和占龙2

作者信息

  • 1. 中国医学科学院/北京协和医学院基础医学研究所系统医学中心,北京 100005
  • 2. 中国医学科学院/北京协和医学院医学生物学研究所,云南昆明 650118
  • 折叠

摘要

Abstract

Ferrets play an important role in influenza virus research,and the ferrets are used as an animal model for the study of influenza because they are most susceptible to human influenza viruses and develop some of the symptoms of influenza that are similar with humans.The ferrets are ideal animal models in the research of mechanism,transmission and vaccine evaluation of influenza virus.The correct and standard operations have important influence to the result of the research.Here,we carried on the exploratory re-search of influenza virus infection model in ferrets about grabbing,anesthesia,virus infection,nasal wash and heart blood collection,clinical symptom record and tissue harvest according to reported actual opera-tion and relevant literature,and built the standard laboratory procedures preliminary.The research has strong practicability and manipuility,and important reference value for other researchers.

关键词

雪貂/流感病毒/感染

Key words

ferret/Influenza virus/infection

分类

农业科技

引用本文复制引用

张涛,徐娟,杨凤梅,秦晓峰,程根宏,和占龙..流感病毒感染雪貂的标准化操作程序建立[J].动物医学进展,2014,(10):25-29,5.

基金项目

云南省应用基础研究基金项目(2013FZ142);云南省技术创新人才培养基金项目 ()

动物医学进展

OA北大核心CSTPCD

1007-5038

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