动物医学进展Issue(1)：53-56,4.
内毒素对大鼠小肠黏膜组织的影响及多价阳离子 A 的保护效应
Influence of Endotoxin on Small Intestinal Mucosa and Protective Effects of CA in Rats
摘要
Abstract
This study was to explore the influence of endotoxin (ET) on small intestinal mucosa tissue and the protective effects of CA in rats .72 SD rats were randomly divided into three groups :the control group , ET group and CA group ,after appropriate treatment the duodenum ,jejunum tissue were collected and tested at 3 ,4 ,8 ,12 h .The pathological slices of above tissues were prepared and stained by H .E .,then were analyzed by graphical analysis system .The length of the intestinal villi of the duodenum and jejunum in ET group were shorter than in control and CA group at 3 ,4 ,8 ,12 h (P<0 .01) .The quantity of IEL in the duodenum and jejunum in ET group were less than that of control and CA group at 3 ,4 ,8 ,12 h (P<0 .01) .The quantities of IEL in the duodenum and jejunum in CA group were more than that of ET group at 4 ,8 ,12 h (P<0 .01) .The results indicated that ET could destroy the normal structures of small intestine ,reduce the length of the intestinal villi ,and consequently affect the normal absorptive and im‐mune function .However ,CA has protective effects by significantly relieving the toxic effects of ET .关键词
内毒素/阳离子A/小肠绒毛长度/上皮内淋巴细胞/大鼠Key words
endotoxin/cation A/length of intestinal villus/intrepithelial lymphocyte/rat分类
农业科技引用本文复制引用
严玉霖,高洪,卢琴,王修庚,赵汝,陈玲..内毒素对大鼠小肠黏膜组织的影响及多价阳离子 A 的保护效应[J].动物医学进展,2015,(1):53-56,4.基金项目
国家自然科学基金项目（30560113）；云南省现代农业生猪产业技术体系建设项目（云财农［2010］119号）；云南省高校科技创新团队支持计划资助项目 （）
