南方医科大学学报Issue(1)：141-145,5.DOI:10.3969/j.issn.1673-4254.2015.01.29
基质诱导的自体软骨移植术后3T磁共振T2mapping成像对移植软骨的分层定量评价
3T magnetic resonance T2 mapping for evaluation of cartilage repair after matrix-associated autologous chondrocyte transplantation
张君 1徐贤 1李雪 1陈敏 1董天明 1左盼利 2安宁豫1
作者信息
- 1. 中国人民解放军总医院南楼放射科，北京 100853
- 2. 西门子 中国 有限公司医疗业务领域磁共振事业部，北京100102
- 折叠
摘要
Abstract
Objective To assess the value of magnetic resonance imaging (MRI) T2 mapping in quantitative evaluation of cartilage repair following matrix-associated autologous chondrocyte transplantation (MACT). Methods Six patients (with 9 plug cartilages) following MACT underwent MRI on a 3.0 Tesla MR scan system at 3, 6 and 12 months after the surgery. The full-thickness and zonal areas (deep and superficial layers) T2 values were calculated for the repaired cartilage and control cartilage. Results The mean T2 values of the repaired cartilage after MACT were significantly higher than that of the control cartilages at 3 and 6 months (P<0.05), but not at 12 months (P=0.063). At 6 and 12 months, the T2 values of the superficial layers were significantly higher than those of the deep layers in the repaired cartilages (P<0.05). The zonal (deep and superficial layers) T2 values of the repaired cartilages decreased significantly over time at 6 and 12 months as compared to those at 3 months after the surgery (P<0.05). Conclusion MRI T2 mapping can serve as an important modality for assessing the repair of the articular cartilage following MACT.关键词
软骨修复/基质诱导的自体软骨细胞移植/磁共振成像/T2mappingKey words
cartilage repair/matrix-associated autologous chondrocyte transplantation/magnetic resonance imaging/T2 mapping引用本文复制引用
张君,徐贤,李雪,陈敏,董天明,左盼利,安宁豫..基质诱导的自体软骨移植术后3T磁共振T2mapping成像对移植软骨的分层定量评价[J].南方医科大学学报,2015,(1):141-145,5.
