南方医科大学学报Issue(1)：154-159,6.DOI:10.3969/j.issn.1673-4254.2015.01.32
基于3.0 T高分辨率磁共振成像的大脑中动脉粥样硬化性狭窄研究进展
Intracranial atherosclerotic middle cerebral arterial stenosis research based on 3.0 Tesla high-resolution magnetic resonance imaging:recent progress
摘要
Abstract
Intracranial atherosclerotic disease (ICAD) of a major intracranial artery, including middle cerebral artery (MCA), basilar artery, is the most common causes of stroke and is associated with a high risk of recurrent stroke in China. The difficulty to treatment these high-risk disease is to identify high-risk stroke subgroups and to develop more effective treatments (aggressive medical therapy/endovascular therapy). With the benefits, including non-invasive, in vivo, and no-ionizing radiation, 3.0 Tesla high-resolution magnetic resonance imaging (HR MRI) could be used to stratify high-risk patients, monitor progression of disease, and evaluate clinical efficacy, based on MCA wall structure and plaque characteristic. HR MRI has the latency of predicting high-risk patients benefit from endovascular therapy, having a broad application prospect during psot-SAMMPRIS era. The current research on MCA stenosis using HR MRI focuses on methodology, diagnosis and differential diagnosis, etiology, and lacks of clinical efficiency evaluation and prognostic analysis of ICAD treatment, especially lacks the research on in-stent restenosis, which needs further investigation.关键词
颅内动脉狭窄/动脉粥样硬化/高分辨MR管壁成像/大脑中动脉/斑块/血管壁Key words
intracranial arterial stenosis/atherosclerosis/high-resolution magnetic resonance imaging/middle cerebral artery/plaque/vessel wall引用本文复制引用
贾泽军,赵瑞,杨志刚,黄清海,邓晓群,洪波,刘建民..基于3.0 T高分辨率磁共振成像的大脑中动脉粥样硬化性狭窄研究进展[J].南方医科大学学报,2015,(1):154-159,6.基金项目
国家自然科学基金（31370810）；上海市市级医院新兴前沿技术联合攻关项目（ SHDC12012103）；上海市卫计委青年基金（20144Y0201）Supported by National Natural Science Foundation of China (31370810) （31370810）
