南方医科大学学报Issue(2)：272-275,4.DOI:10.3969/j.issn.1673-4254.2015.02.24
连续性血液净化治疗体外循环堵管风险积分模型的构建
A prognostic model for predicting extracorporeal circuit clotting in patients with continuous renal replacement therapy
摘要
Abstract
Objective To establish a prognostic model for predicting extracorporeal circulation clotting in patients with continuous renal replacement therapy(CRRT). Methods 425 patients with CRRT were involved in the study. We built a predictive risk model of extracorporeal blood clotting with the 302 participants, and 103 participants were used to validate the model. The primary endpoint of CRRT was extracorporeal circulation pipe blockage. Results We used a score of 0-5 point evaluating system to predict the risk of 24 hours CRRT integral model of cardiopulmonary bypass clogging. The area under the CRRT predictive model of cardiopulmonary bypass clogging integral system ROC curve was 0.790 (95%CI 0.719-0.826)(P<0.001). The evaluating system can determine the blockage of 24 hours CRRT extracorporeal circulation. The results showed that CRRT extracorporeal plugging prediction fitted the integral model and could predict the chance of plugging. The actual plugging rate showed no significant difference from the predicted rate (R2=0.301, P=0.232). The cardiopulmonary pipe survival time between the 3 groups(low risk, intermediate risk, and high risk) showed a significant difference (P<0.05). Conclusion We established a continuity extracorporeal blood purification plugging risk score model, to predict plugging risks during CRRT treatment.关键词
连续性血液净化/体外循环/凝血/积分模型Key words
continuous blood purification/extracorporeal circuit/clotting/integral model引用本文复制引用
何朝生,符霞,梁馨苓,宋利,史伟..连续性血液净化治疗体外循环堵管风险积分模型的构建[J].南方医科大学学报,2015,(2):272-275,4.基金项目
国家十二五科技支撑项目（2011BAI10B08）；广东省科技计划项目 （）
