南方医科大学学报Issue(4)：578-582,5.
预防性抗生素在导管室进行完全经皮穿刺主动脉覆膜支架植入术的应用
Prophylactic antibiotics:a necessity in totally percutaneous thoracic endovascular aortic re-pair?
摘要
Abstract
Objective To study the benefit of prophylactic antibiotics (PA) in totally percutaneous aortic endovascular repair (PEVAR) in the catheterization laboratory for reducing stent-graft infection and postimplantation syndrome (PIS). Methods The clinical data were analyzed of patients undergoing thoracic endovascular aortic repairs. The patients were divided into non-PA group and PA group according to the use of prophylactic antibiotics before PEVAR. The diagnosis of infection was made by two senior physicians with reference to Hospital Acquired Infection Diagnostic Criteria Assessment released by the Ministry of Health of China. Results The 95 enrolled patients included 35 with PA and 60 without PA group, who were comparable for baseline characteristics. Infection-related deaths occurred in 1 case in non-PA group and retrograde Stanford type A dissection and death occurred in 1 case in PA group (1.67%vs 2.85%, P=1.00). The PA and non-PA groups showed no significant difference in the incidence of postoperative infection (5%vs 2.86%, P=1.000), hospital stay (9.30±7.21 vs 10.06±5.69, P=0.094), infection-related mortality (1.67% vs 0%, P=1.00), or postoperative fever (70.90% vs 91.43%, P=0.20). The body temperature showed significant variations at different time points after procedure (F=19.831, P<0.001) irrelevant to the use of prophylactic antibiotics (F=0.978, P=0.326). Conclusion The current data do not support the benefit of PA in reducing postoperative infection and PIS in patients undergoing PEVAR, but the patients without PA may have worse clinical outcomes in the event of postoperative infections.关键词
主动脉夹层/腔内修复/感染/腔内修复术后综合征/预防性抗生素Key words
aortic dissection/endovascular repair/infection/postimplantation syndrome/prophylactic antibiotics引用本文复制引用
谢年谨,罗建方,罗淞元,薛凌,李威,谷梦楠,刘媛,黄文晖,范瑞新,陈纪言..预防性抗生素在导管室进行完全经皮穿刺主动脉覆膜支架植入术的应用[J].南方医科大学学报,2015,(4):578-582,5.基金项目
广东省科技计划项目 （）
