南方医科大学学报Issue(5):716-719,4.DOI:10.3969/j.issn.1673-4254.2015.05.18
高中心动脉脉压水平与慢性腹膜透析病人的心血管疾病相关
High central pulse pressure level is associated with cardiovascular disease in patients receiving maintenance peritoneal dialysis
摘要
Abstract
Objective To evaluate the association between central pulse pressure level and cardiovascular diseases (CVD) in patients receiving maintenance peritoneal dialysis. Methods This cross-sectional study was conducted in 234 patients on maintenance peritoneal dialysis. Central pulse pressure levels were measured using a SphygmoCor analyzer, and cardiovascular diseases were defined as diagnosed ischemic heart disease, heart failure, stroke or peripheral vascular disease. Results The central pulse pressure levels of patients with CVD were significantly higher than those without CVD (51.7±22.5 vs 43.7 ± 17.8 mmHg, P=0.004), while the brachial pulse pressure levels were comparable between the two patient groups. After adjusting for brachial pulse pressure and other relevant risk factors, central pulse pressure level was found to independently associate with CVD (adjusted OR=1.33, 95%CI 1.01-1.73, P=0.04 ). Conclusion High central pulse pressure level may serve as a risk factor for CVD in patients on maintenance peritoneal dialysis.关键词
中心动脉脉压/心血管疾病/腹膜透析Key words
central pulse pressure/cardiovascular diseases/peritoneal dialysis引用本文复制引用
杨小兵,郭东风,蒋建平..高中心动脉脉压水平与慢性腹膜透析病人的心血管疾病相关[J].南方医科大学学报,2015,(5):716-719,4.基金项目
国家自然科学基金(81470995);广东省自然科学基金(2014A030313345) Supported by National Natural Science Foundation of China(81470995) (81470995)