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半导体聚合物纳米荧光探针的制备及生物应用研究进展

张佳楠 常开文 李琼 孙凯 尹升燕 吴长锋

发光学报Issue(7):725-737,13.
发光学报Issue(7):725-737,13.DOI:10.3788/fgxb20153607.0725

半导体聚合物纳米荧光探针的制备及生物应用研究进展

Preparation, Regulation and Biological Application of Fluorescent Semiconducting Polymer Dots

张佳楠 1常开文 1李琼 1孙凯 1尹升燕 1吴长锋1

作者信息

  • 1. 集成光电子学国家重点联合实验室吉林大学实验区 吉林大学电子科学与工程学院,吉林 长春 130012
  • 折叠

摘要

Abstract

In recent years, fluorescent semiconducting polymer nanoparticles, which primarily con-sist of π-conjugated polymers, have been attracted considerable attention in an extensive range of applications, such as fluorescence imaging and biosensing. These π-conjugated polymer nanoparti-cles are called polymer dots ( Pdots) when they have particle size comparable to that of the inorganic quantum dots. Pdots have many charming properties, such as large absorption cross section, high fluorescence quantum yield, very fast emission rates, excellent photostability, and so on. In this re-view, we briefly summarize recent findings of the photophysical properties of Pdots, the surface func-tionalization and biomolecular conjugation of Pdots and their applications in cellular labeling, in vivo imaging, biosensing, single-particle tracking, drug delivery and photodynamic therapy.

关键词

半导体聚合物/量子点/荧光探针/单粒子示踪/生物成像

Key words

semiconducting polymer/quantum dots/fluorescent probes/single particle tracking/biological imaging

分类

数理科学

引用本文复制引用

张佳楠,常开文,李琼,孙凯,尹升燕,吴长锋..半导体聚合物纳米荧光探针的制备及生物应用研究进展[J].发光学报,2015,(7):725-737,13.

基金项目

国家自然科学优秀青年基金(61222508) (61222508)

国家自然科学重点基金(61335001)资助项目 (61335001)

发光学报

OA北大核心CSCDCSTPCD

1000-7032

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