分析化学Issue(8)：1077-1082,6.DOI:10.11895/j.issn.0253-3820.140187
表面形貌对螺旋线形跨尺度电化学葡萄糖传感器性能的影响
Relationship Between Surface Morphology and Performance of a Spirally Hierarchical Structure-based Electrochemical Glucose Sensor
摘要
Abstract
Zinc oxide nanowires were hydrothermally synthesized on the surface of an Au cylindrical spiral formed by manually spiraling an Au fiber around an optical fiber core, glucose oxidase was immobilized on these nanowires by physical adsorption, and then a spirally hierarchical structure-based glucose enzymatic electrode was obtained. The surface morphologies of the spirally hierarchical structures and corresponding enzymatic electrodes were extracted, and the electrochemical performances of the enzymatic electrodes were characterized. It was concluded that the synthesizing parameters of zinc oxide nanowires significantly affected the surface morphologies and glucose oxidase immobilization on the spirally hierarchical structures, and further the performances of related glucose sensors. With Zn2﹢concentration of the growth solution set at 25 mmol/L, the roughness of surface morphology was determined to be 0. 10 μm and correlation length 0. 29 μm, resulting in a better immobilization of glucose oxidase upon zinc oxide nanowires. In this case the sensitivity of the glucose sensor was determined to be 2. 15 μA/(mmol/L·cm2), the linear range was 0-4. 50 mmol/L, the low detection limit was 9. 20 μmol/L and Michaelis-Menten constant was 3. 68 mmol/L. The results not only benefit the batch production of the spirally hierarchical structure-based enzymatic electrodes, but also significantly improve the performances of the glucose sensors.关键词
跨尺度结构/表面形貌/葡萄糖生物传感器/循环伏安法/计时电流法Key words
Hierarchical structure/Surface morphology/Glucose biosensor/Cyclic voltammetry/Amperometric response引用本文复制引用
景蔚萱,周帆,成妍妍,齐含,陈路加,蒋庄德,王兵..表面形貌对螺旋线形跨尺度电化学葡萄糖传感器性能的影响[J].分析化学,2014,(8):1077-1082,6.基金项目
本文系国家自然科学基金(No.51075324)、国家自然科学基金“纳米制造的基础研究”重大研究计划(No.91323303)、国家重大科学仪器设备开发专项子任务(No.2012YQ03026101)和长江学者和创新团队发展计划(No. IRT1033)资助@@@@This work was supported by the the National Natural Science Foundation of China (No.51075324), the NSFC Major Research Plan on Nano-manufacturing (No.91323303), the National Key Scientific Instrument and Equipment Development Projects of China (No.2012YQ03026101) and the Program of Chang Jiang Scholars and Innovative Research Team in University (No. IRT1033) （No.51075324）
