分析化学Issue(9)：1281-1287,7.DOI:10.11895/j.issn.0253-3820.140172
固相萃取-超高效液相色谱串联质谱法测定饮用水中15种邻苯二甲酸酯
Determination of 15 Phthalate Esters in Drinking Water by Solid Phase Extraction-Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
A method of solid phase extraction coupled with ultra performance liquid chromatography-tandem mass spectrometry ( SPE-UPLC/MS/MS) was developed for the determination of 15 phthalate esters. Drinking water samples were concentrated by C18 SPE cartridge. The fifteen phthalate esters were separated on a phenyl column with gradient elution using methanol and water as mobile phases. Multiple reaction monitoring ( MRM) acquisition under positive ion mode was performed. The external matrix standard solutions were used for the quantitative determination. The linear range of Di-n-butyl phthalate was 0. 63-1000 μg/L. The other 14 phthalate esters showed good linearity in the range of 0 . 002-500 μg/L with the correlation coefficients more than 0. 9970. The limits of quantification ( LOQ) were 2. 2-632 ng/L. The spiked recoveries ranged from 81 . 3% to 109%. The relative standard deviations were less than 14%.关键词
饮用水/邻苯二甲酸酯/固相萃取/超高效液相色谱串联质谱Key words
Drinking water/Phthalate esters/Solid phase extraction/Ultra performance liquid chromatography-tandem mass spectrometry引用本文复制引用
张海婧,胡小键,林少彬..固相萃取-超高效液相色谱串联质谱法测定饮用水中15种邻苯二甲酸酯[J].分析化学,2014,(9):1281-1287,7.基金项目
卫生行业科研专项项目(No.201002001)资助 （No.201002001）
