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微流控芯片上高电导率介质中聚苯乙烯微球的动电分离

宋宁宁 张昊 李金波 甄军晖 高健

分析化学Issue(2):176-180,5.
分析化学Issue(2):176-180,5.DOI:10.11895/j.issn.0253-3820.140804

微流控芯片上高电导率介质中聚苯乙烯微球的动电分离

Electrokinetic Separation of Polystyrene Microspheres in Conductive Media on a Microfluidic Chip

宋宁宁 1张昊 1李金波 1甄军晖 2高健1

作者信息

  • 1. 齐鲁工业大学化学系,济南250353
  • 2. 山东大学医学院,济南250012
  • 折叠

摘要

Abstract

A polydimethylsiloxane ( PDMS )/glass microfluidic chip consisting of a three-layer sandwich structure and three-parallel micro-electrode system was fabricated for the separation of polystyrene microspheres according to the particle size in high conductive solution by electric field produced by alternating current. The principle of electrokinetics of microspheres directional movement was investigated. The results showed that, when the applied voltage was 14 V at 100 kHz, the separation efficiency of 10 and 25 μm polystyrene microspheres was the best. Similarly, with a voltage of 10 V at 2 MHz, the separation efficiency of 5 and 25 μm polystyrene microspheres could achieve the highest value. Meanwhile, the voltage of 11 V at 1 MHz was suitable for the separation of 5 , 10 and 25 μm polystyrene microspheres with the separation efficiency of over 90%. At the same time, the formation of the laminar region in the middle of the electrode gap was the key role of microsphere separation.

关键词

微流控芯片/动电技术/高电导率/聚苯乙烯微球

Key words

Microfluidic chip/Electrokinetics/High-conductivity/Polystyrene microspheres

引用本文复制引用

宋宁宁,张昊,李金波,甄军晖,高健..微流控芯片上高电导率介质中聚苯乙烯微球的动电分离[J].分析化学,2015,(2):176-180,5.

基金项目

国家自然科学基金面上项目(No.21375068)、国家自然科学基金青年科学基金项目(No.81400729)、山东省优秀中青年科学家科研奖励基金(No. BS2012SW017)及山东大学基本科研业务费专项资金(No.2014JC033)资助This work was supported by the National Natural Science Foundation of China (Nos.21375068,81400729) (No.21375068)

分析化学

OA北大核心CSCDCSTPCDSCI

0253-3820

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