法医学杂志Issue(3)：211-214,4.DOI:10.3969/j.issn.1004-5619.2015.03.010
福建汉族人群21个常染色体STR基因座的遗传多态性
Genetic Polymorphisms of 21 Autosomal STR Loci of Fujian Han Population
摘要
Abstract
Objective To investigate the genetic polym orphism s of 21 autosom al STR loci of Fujian H an population and evaluate the forensic application value of GlobalFilerTM E xpress kit. Methods A m plified w ith GlobalFilerTM E xpress kit, DNA sam ples were obtained from 741 unrelated individuals of Fujian H an population. The population genetics param eters of 21 autosom al STR loci were calculated. Results The 21 autosom al STR loci were found to be no deviation from Hardy-Weinberg equilibration (P>0.05) and relatively abundant in high polym orphism . H eterozygosity ranged from 0.589 to 0.914, pow er of dis-crim ination ranged from 0.754 to 0.992, polym orphic inform ation content ranged from 0.520 to 0.940, and pow er of exclusion ranged from 0.278 to 0.825. The SE33 locus was the highest degree in poly-m orphism . Conclusion The 21 STR loci of GlobalFilerTM E xpress kit have high value in discrim ination pow er and can be useful in personal identification and paternity test in Fujian H an population.关键词
法医遗传学/多态现象,遗传/GlobalFilerTM Express试剂盒/福建/汉族Key words
forensic genetics/polym orphism , genetic/G lobalFilerTM E xpress kit/Fujian/H an nationality分类
社会科学引用本文复制引用
练惠辉,戈文东,林峰,李斌..福建汉族人群21个常染色体STR基因座的遗传多态性[J].法医学杂志,2015,(3):211-214,4.基金项目
福建省自然科学基金资助项目 （）
