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普鲁卡因局部封闭加胸腺肽治疗神经性皮炎的临床研究

吴定苏 凌韶勤 李晓英 曾抗 詹美伶 练思玉 彭努中

国际医药卫生导报Issue(15):2133-2136,4.
国际医药卫生导报Issue(15):2133-2136,4.DOI:10.3760/cma.j.issn.1007-1245.2015.15.009

普鲁卡因局部封闭加胸腺肽治疗神经性皮炎的临床研究

Partial closure of procaine combined with thymosin in treatment of neurodermatitis

吴定苏 1凌韶勤 2李晓英 2曾抗 3詹美伶 4练思玉 2彭努中2

作者信息

  • 1. 423000 东莞市莞城医院皮肤科
  • 2. 423000 东莞市莞城医院中心门诊
  • 3. 510000 南方医科大学南方医院皮肤科
  • 4. 423000 东莞市莞城医院功能科
  • 折叠

摘要

Abstract

Objective To investigate the efficacy of partial closure of procaine combined with thymosin in the treatment of neurodermatitis.Methods 134 patients with neurodermatitis were randomly divided into an observation group and a control group according to randomized controlled trials, 67 for each group. Thecontrol group were conventionally treated; in addition, the observation group were treated with partial closure of procaine and thymosin. The clinical efifcacies were compared between these two groups.Results 7, 14, 21, and 28 days after the treatment, the total effective rates of the observation group were 7.46%, 80.60%, 94.03%, and 100.00%, respectively, which were signiifcantly higher than those of the control group (0.00%, 22.39%, 43.28%, and 71.64%) (P < 0.05). 3 months after the treatment, the recurrence rate was 0.00% in the observation group and 22.39% (15/67) in the control group, with a statistical difference (P< 0.05). The results of 4 follow-ups and scoring after the treatment showed that pruritus and skin lesions improved more and faster and the total symptom score was signiifcantly lower in the observation group than in the control group, with statistical differences (P < 0.05).ConclusionsPartial closure of procaine combined with thymosin in the treatment of neurodermatitis is effective, can lower recurrence rate and cut the cost down, and is worth being clinically generalized.

关键词

神经性皮炎/普鲁卡因/胸腺肽

Key words

Neurodermatitis/Procaine/Thymosin

引用本文复制引用

吴定苏,凌韶勤,李晓英,曾抗,詹美伶,练思玉,彭努中..普鲁卡因局部封闭加胸腺肽治疗神经性皮炎的临床研究[J].国际医药卫生导报,2015,(15):2133-2136,4.

基金项目

东莞市科技局课题 ()

国际医药卫生导报

1007-1245

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