赣南医学院学报Issue(3):329-331,3.
佛甲草对佐剂性关节炎大鼠氧化应激的影响
The antioxtion effect of Sedum Lineare Thunb on adjuyant arthritis mice
摘要
Abstract
Objectiye:To observe the therapeutic effect of Sedum lineare Thunb(SLT)on adjuvant arthritis and its effects on antioxidation in mice. Method:By establishing rheumatoid arthritis rats model with injecting Freund complete adju-vant,observe the effect of the high and low dosage of SLT to the chronic paw swelling,nitric oxide(NO)content and glu-tathione peroxidase(GSH-Px)activity in serum. Result:Both SLT groups could reduce the swelling of the model rats, change the level of serum NO,which were lower than the model group,whereas the SLT groups increased the activity of serum GSH-Px. Conclusion:SLT had therapeutic action to rheumatoid arthritis rats,and the mechanism probably was that SLT could strengthen the activity of antioxidase,and scavenge oxygen-free radicals.关键词
佛甲草醇提物/佐剂性关节炎/抗氧化作用Key words
Sedum Lineare Thunb/adjuvant arthritis/antioxidation分类
医药卫生引用本文复制引用
曹性玲,麻海娟,喻思,周青,吴丽珍,黄志华..佛甲草对佐剂性关节炎大鼠氧化应激的影响[J].赣南医学院学报,2014,(3):329-331,3.基金项目
江西省卫生厅科技项目 ()