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佛甲草对佐剂性关节炎大鼠氧化应激的影响

曹性玲 麻海娟 喻思 周青 吴丽珍 黄志华

赣南医学院学报Issue(3):329-331,3.
赣南医学院学报Issue(3):329-331,3.

佛甲草对佐剂性关节炎大鼠氧化应激的影响

The antioxtion effect of Sedum Lineare Thunb on adjuyant arthritis mice

曹性玲 1麻海娟 1喻思 1周青 1吴丽珍 1黄志华1

作者信息

  • 1. 赣南医学院机能实验室,江西 赣州 341000
  • 折叠

摘要

Abstract

Objectiye:To observe the therapeutic effect of Sedum lineare Thunb(SLT)on adjuvant arthritis and its effects on antioxidation in mice. Method:By establishing rheumatoid arthritis rats model with injecting Freund complete adju-vant,observe the effect of the high and low dosage of SLT to the chronic paw swelling,nitric oxide(NO)content and glu-tathione peroxidase(GSH-Px)activity in serum. Result:Both SLT groups could reduce the swelling of the model rats, change the level of serum NO,which were lower than the model group,whereas the SLT groups increased the activity of serum GSH-Px. Conclusion:SLT had therapeutic action to rheumatoid arthritis rats,and the mechanism probably was that SLT could strengthen the activity of antioxidase,and scavenge oxygen-free radicals.

关键词

佛甲草醇提物/佐剂性关节炎/抗氧化作用

Key words

Sedum Lineare Thunb/adjuvant arthritis/antioxidation

分类

医药卫生

引用本文复制引用

曹性玲,麻海娟,喻思,周青,吴丽珍,黄志华..佛甲草对佐剂性关节炎大鼠氧化应激的影响[J].赣南医学院学报,2014,(3):329-331,3.

基金项目

江西省卫生厅科技项目 ()

赣南医学院学报

1001-5779

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