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肥大细胞对特发性眼眶炎性假瘤纤维化的作用研究

曾祥云 袁思奇 刘琳琳 谭述香 谢招莲 黄彬红 高艳芳

赣南医学院学报Issue(4):491-493,3.
赣南医学院学报Issue(4):491-493,3.

肥大细胞对特发性眼眶炎性假瘤纤维化的作用研究

Role of Mastocyte in the Fibrillation of Idiopathic Orbital Inflammatory Pseudotumor

曾祥云 1袁思奇 1刘琳琳 1谭述香 1谢招莲 1黄彬红 1高艳芳1

作者信息

  • 1. 赣南医学院 第一附属医院,江西 赣州 341000
  • 折叠

摘要

Abstract

Objective:To investigate the role of mastocyte(MC)in the proliferation of fibroblast in Idiopathic Orbital In-flammatory Pseudotumor(IOIP). Methods:Rat bone marrow mastocyte and fibroblast were separated and purified,and then cultured them together and respectively. Cell morphology and cell number were observed and analyzed to investigate the role of MC in the proliferation of fibroblast. Results:Proliferation of fibroblast was significantly enhanced by culturing together with MC and cell number of MC was also significantly increased during compound culturing. There was statisti-cally significant difference(P ﹤ 0. 01). Conclusion:MC significantly promotes the proliferation of fibroblast and plays a crucial role during fibrillation in IOIP.

关键词

特发性眼眶炎性假瘤/肥大细胞/成纤维细胞

Key words

Idiopathic Orbital Inflammatory Pseudotumor/mastocyte/fibroblast

分类

医药卫生

引用本文复制引用

曾祥云,袁思奇,刘琳琳,谭述香,谢招莲,黄彬红,高艳芳..肥大细胞对特发性眼眶炎性假瘤纤维化的作用研究[J].赣南医学院学报,2014,(4):491-493,3.

基金项目

江西省自然科学基金资助项目,项目编号20114BAD205068 ()

赣南医学院学报

1001-5779

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