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人工肝 PDF 与 PE + CHDF在晚期肝衰竭治疗中的疗效对比

周观林 张伦理 刘春文 杨沛华 张琼 谢志军

赣南医学院学报Issue(4):527-529,3.
赣南医学院学报Issue(4):527-529,3.

人工肝 PDF 与 PE + CHDF在晚期肝衰竭治疗中的疗效对比

Efficacy Comparison between Artificial Liver PDF and PE + CHDF in the Treatment of Late Liver Failure

周观林 1张伦理 2刘春文 1杨沛华 1张琼 3谢志军3

作者信息

  • 1. 赣州市第五人民医院肝病科,江西 赣州 341000
  • 2. 南昌大学第一附属医院感染科,江西 南昌 330000
  • 3. 赣南医学院第一附属医院消化内科,江西 赣州 341000
  • 折叠

摘要

Abstract

Objective:To evaluate and compare the efficacy of the artificial liver Plasma filtration dialysis(PDF)mode and plasma exchange(PE)plus continuous hemofiltration dialysis(CHDF)mode in the treatment of the end-stage liver failure. Methods:40 patients with the end-stage liver failure were selected and randomly divided into observation group and control group;on the basis of comprehensive treatment the observation group was given PDF medical treatment where-as the control group was given PE plus CHDF therapy. The biochemical improvement of liver function and the three-month mortality before and after the treatment were observed and compared. Results:The control group had the better biochemi-cal improvement than observation group(P ﹥ 0. 05),but the two groups had the same three-month mortality. Conclusion:PE plus CHDF therapy on the basis of comprehensive treatment can get a better improvement in renal function and dehy-dration effects than PDF therapy mode,while there is no difference between the PDF therapy and PE plus CHDF therapy on liver function improvement. But the PDF therapy on the basis of comprehensive treatment can save the therapy time and treatment costs than PE plus CHDF therapy mode. There is no difference between the PDF therapy and PE plus CHDF therapy on the three-month mortality.

关键词

人工肝血浆滤过透析/人工肝血浆置换 + 血液滤过透析/晚期肝衰竭/疗效

Key words

PDF/PE plus CHDF/end-stage liver failure/efficacy

分类

医药卫生

引用本文复制引用

周观林,张伦理,刘春文,杨沛华,张琼,谢志军..人工肝 PDF 与 PE + CHDF在晚期肝衰竭治疗中的疗效对比[J].赣南医学院学报,2014,(4):527-529,3.

基金项目

江西省科技计划项目,编号2011ZBBG70042 ()

赣南医学院学报

1001-5779

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