赣南医学院学报Issue(1)：33-35,3.DOI:10.3969/j.issn.1001-5779.2015.01.0010
维生素E微胶囊的制备工艺研究
Study on Preparation Technology of Vitamin E Microcapsules by Ultrasound
敖慧君 1黄清松2
作者信息
- 1. 广州市红十字会医院药学部
- 2. 广东药学院，广东 广州 510220
- 折叠
摘要
Abstract
Objective:To study the optimum conditions of the ultrasonic preparation of vitamin E oil-β-Cyclodextrin in-clusion complexes via optimizing the inclusion process parameters by orthogonal design.Methods:Beta-Cyclodextrin was used as wall materials.Inclusion complexation was applied to the microencapsulation of vitamin E.Results:The opti-mum condition was determined by orthogonal design and the results were as follows:the ultrasonic power was 150W with duration time of 20 min,and m (VE):m (β-cyclodextrin)=1∶9 at 30 ℃.Under the condition of the optimal selec-tion of inclusion,the inclusion rate was 83.5% and the product yield was 71.3 %.Conclusion:Under the condition, the vitamin E oil-β-Cyclodextrin inclusion complexes successfully solve the problem that vitamin E is easy to be oxidized and is instable with light and heat.It improves the stability.关键词
维生素E/β-环糊精/微胶囊Key words
VE/β-cyclodextrin/microcapsule分类
化学化工引用本文复制引用
敖慧君,黄清松..维生素E微胶囊的制备工艺研究[J].赣南医学院学报,2015,(1):33-35,3.
