赣南医学院学报Issue(1)：149-152,4.DOI:10.3969/j.issn.1001-5779.2015.01.057
miRNAs对阿尔茨海默病淀粉样蛋白产生和tau蛋白代谢作用的研究进展
Research Progress of MiRNAs'Effects on Amyloid-beta Production and Tau Metabolism in Alzheimer
周付涛 1陈双容 2谭波涛1
作者信息
- 1. 浙江丽水学院医学与健康学院，浙江 丽水 323000
- 2. 浙江丽水学院工程与设计学院，浙江 丽水 323000
- 折叠
摘要
Abstract
MiRNA is a class of small,noncoding RNAs of 21 ~23 nucleotides that regulate gene expression at the postt-ranscriptional level by binding to the mRNA of protein-coding genes.In recent years,roles of miRNAs in Alzheimer's dis-ease pathogenesis have been paid wide attentions.This article reviews the lately progress in the effects of miRNAs on am-yloid-beta production and the microtubule-associated protein tau metabolism,which supplies a reference for further study on AD.关键词
miRNA/β淀粉样蛋白/Tau蛋白/阿尔茨海默病Key words
miRNA/amyloid-beta/Tau protein/Alzheimer's disease分类
医药卫生引用本文复制引用
周付涛,陈双容,谭波涛..miRNAs对阿尔茨海默病淀粉样蛋白产生和tau蛋白代谢作用的研究进展[J].赣南医学院学报,2015,(1):149-152,4.
