感染、炎症、修复Issue(3)：169-173,5.DOI:10.3969/j.issn.1672-8521.2014.03.012
2010-2013年某三甲医院住院患者抗真菌药物应用分析
Analysis on the utilization of antifungal agents in in-patients in a third-grade and class-A hospital during 2010 to 2013
王芳 1邸勇1
作者信息
- 1. 解放军总医院第一附属医院药剂药理科，北京 100048
- 折叠
摘要
Abstract
Objective:To analyze the utilization of antifungal agents in patients admitted to the First Hospital Af-filiated to the Chinese PLA General Hospital during 2010 to 2013,and to provide references for clinical drug use. Methods:The data on utilization of antifungal agents in patients admitted to the First Hospital Affiliated to the Chinese PLA General Hospital during 2010 to 2013 were analyzed by sequencing the sales expenditure and defined daily dose system (DDDs)of antifungal agents,the antibacterial use density(AUD)and sequenced ratio were cal-culated. Results:During 2010 to 2013,antifungal sales expenditure showed an increasing trend,and the annual average growth rate was 24.14%. During 2010 to 2012,the annual average sales expenditure of pyrrole antifungal drugs was in the first place,and it was replaced by echinocandins in 2013. Pyrrole antifungal drugs were domi-nantly used in anti-fungi treatment. The sales expenditure of voriconazole gradually replaced itraconazole to be-come the first. However,the itraconazole kept on the top of DDDs list. The drug use intensity of antifungal a-gents showed a declining trend in these years. Conclusions:The sales of antifungal agents in in-patients showed a steady raise during 2010 to 2013 in our hospital. However,the drug use intensity is on the decline. In general,the structure and intensity of utilization of antifungal agents were rational on the whole. Itraconazole and voriconazole are still the major antifungal agents in the treatment of fungal infections of inpatients. At the same time,the treat-ment effectiveness of echinocandins is gradually recognized by clinicians.关键词
抗真菌药物/应用分析/消耗金额Key words
Antifungal agents/Application analysis/Sales expenditure引用本文复制引用
王芳,邸勇..2010-2013年某三甲医院住院患者抗真菌药物应用分析[J].感染、炎症、修复,2014,(3):169-173,5.
