感染、炎症、修复Issue(4)：229-231,3.DOI:10.3969/j.issn.1672-8521.2014.04.012
右美托咪啶对行纤维支气管镜检查的重症患者心脏功能的影响
Effect of dexmedetomidine on cardiac function of critically ill patients during fiberoptic bronchoscopy
摘要
Abstract
Objective:To observe the effect of dexmedetomidine on heart rate,mean arterial pressure and electro-cardiogram (ECG)in critically ill patients during fiberoptic bronchoscopy. Methods:Fifty patients,admitted to ICU from May 2013 to May 2014 and undergoing fiberoptic bronchoscopy,were randomly divided into two groups:control group(n=25)and dexmedetomidine group (n=25). In patients of dexmedetomidine group,aero-sol inhalation of 2% idocaine 10 ml was given 15 minutes before bronchoscopy,and a loading dose of dexmedeto-midine 1μg/kg was injected intravenously within 10 minutes before bronchoscopy,followed by intravenous infu-sion of 0.2-0.4μg·kg-1 ·h-1 until the end of bronchoscopy. In the control group,patients only received aero-sol inhalation of 2% idocaine 10 ml. The heart rate,mean arterial pressure and changes in ST-T of ECG before and after bronchoscopy were observed.Results:In patients of the control group,a significant increase in heart rate and mean arterial pressure were observed(P<0.05),while in the dexmedetomidine group,the patient’s heart rate and mean arterial pressure increased only slightly after bronchoscopy(P>0.05),and the difference was not signif-icant compared to those before bronchoscopy(P>0.05). Changes in ST-T of ECG was higher than 5 mV in 5 ca-ses of the dexmedetomidine group,but it was observed in 1 5 cases in the control group,the difference was signifi-cant(P<0.05). Conclusions:For critically ill patients with bronchoscopy,administration of dexmedetomidine can stabilize the patient's circulatory system and protect myocardium against stress.关键词
右美托咪啶/纤维支气管镜/血压/心电图Key words
Dexmedetomidine/Bronchoscopy/Blood pressure/Electrocadiogram引用本文复制引用
孙瑞玥,胡秋善,郑伟..右美托咪啶对行纤维支气管镜检查的重症患者心脏功能的影响[J].感染、炎症、修复,2014,(4):229-231,3.
