甘肃医药Issue(6)：413-415,3.
甘肃250名汉族人甘露糖结合凝集素基因多态性分析
Analysis of mannan-binding lectin gene polymorphisms in 250 individuals of Han nationality in Gansu province
摘要
Abstract
Objective:To analyse mannan-binding lectin (MBL) gene polymorphisms of Han nationality in Gansu province in order to further research about relationship of MBL gene mutation and diseases . Methods: Three polymorphic loci in MBL of 250 healthy Chinese Han individuals from Gansu province were analyzed by PCR-SSP in which the genotype and allele frequency of MBL in different Han population from China were compared . Results: We only found the A and B allele . The genotype frequencies of MBL gene were 74.80%(GGC/GGC),22.00%(GGC/GAC) and 3.20%(GAC/GAC).The allele frequencies of MBL gene were 0.858 (GGC),0.142(GAC). Conclusion: The distribution of polymorphism in MBL gene is consistent with the Hardy-Weinberg equilibrium which is significantly different among the Han population of others areas .关键词
甘露糖结合凝集素/汉族/甘肃/基因多态性Key words
MBL/gene polymorphisms/Gansu/Han nationality引用本文复制引用
王海军,何莉莉,居军,张兴旺..甘肃250名汉族人甘露糖结合凝集素基因多态性分析[J].甘肃医药,2014,(6):413-415,3.基金项目
甘肃省中青年科技基金计划资助项目 （）
