摘要
Abstract
Distribution and relative fators of hepatitis B vaccination and marker of hepatitis B virus were observed in children under 15 years old, which provide scientific data for prevention. Methods:Cluster sampling and stratified random sampling were used to selected 1260 individuals under 15 years old from 7 towns for study in which HBsAg, anti-HBs, anti-HBc and other HBV infection markers were respectively detected,and questionnaire investigation, examination of vaccination certificate or card were used to assess hepatitis B vaccination rate. Results:HbsAg, anti-HBs, anti-HBc positive rates and HBV infection rate in children under 15 years old respectively were 0.95%, 78.97%, 5.16%and 6.98%, which was increased with age(P<0.05). Hepatitis B vaccine coverage rate was 90.95%, which was reduced with age(χ2=60.596, P=0.000). Conclusion:HBV infection rate is a lower level in children under 15 years old. Levels of protective antibodies to hepatitis B are reduced with age. Hepatitis B vaccination is a protective factor for hepatitis B virus infection, but age is a risk factor.关键词
乙肝病毒标志物/血清流行病学/影响因素/乙肝疫苗Key words
hepatitis B virus markers/seroepidemiology/relative factors/hepatitis B vaccine