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人类疱疹病毒6型在口腔鳞癌组织中的表达

田彩平 姚伯程 王芳 张莉芹

甘肃医药Issue(1):1-3,3.
甘肃医药Issue(1):1-3,3.

人类疱疹病毒6型在口腔鳞癌组织中的表达

Expression of Human herpesviruses 6 in Tissues of Oral squamous carcinoma

田彩平 1姚伯程 1王芳 1张莉芹2

作者信息

  • 1. 730050 甘肃 兰州,甘肃省医学科学研究院医学分子生物学研究中心
  • 2. 730050 甘肃 兰州,甘肃省肿瘤医院门诊口腔科
  • 折叠

摘要

Abstract

Objective: To investigate the the relationship between HHV-6 infection and the incidence of oral squamous cell carcinomas . Methods: Detected the expression level of HHV-6 mRNA and it's protein in tissues of oral squamous carcinoma with real -time PCR and immunohistochemistry technologies . Results: The expression rates of HHV-6 mRNA in tissues of oral squamous carcinoma and normal oral mucosa were 83.3% and 13.9% respectively (P<0.05). As well as the expression rates of HHV-6 protein were 86.1% and 0 respectively (P<0.05). Therefore, we concluded that the expression level of HHV-6 mRNA and it's protein in tissues of oral squamous carcinoma and normal oral mucosa had significantly difference . Conclusion: The incidence of oral squamous cell carcinomas has significant correlation with HHV-6 infection .

关键词

HHV-6/口腔鳞癌组织/实时定量PCR/免疫组织化学

Key words

HHV-6/The tissues of oral squamous cell carcinoma/Real-time PCR/Immunohistochemistry

引用本文复制引用

田彩平,姚伯程,王芳,张莉芹..人类疱疹病毒6型在口腔鳞癌组织中的表达[J].甘肃医药,2015,(1):1-3,3.

基金项目

甘肃省科技支撑计划资助项目(编号:1104FKCA134);甘肃省中医药管理局课题(编号GZK-2012-24);甘肃省肿瘤医院;甘肃省医学科学研究院中青年科技人才创新工程项目 ()

甘肃医药

1004-2725

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