广东药学院学报Issue(4)：404-407,4.DOI:10.3969/j.issn.1006-8783.2014.04.003
全天麻咀嚼胶体外释放度的测定
In vitro dissolution of gastrodine in Gastrodia elata chewing gums
摘要
Abstract
Objective To evaluate the in vitro dissolution of gastrodine chewing gum. Method The content of gastrodine in Gastrodia elata chewing gum was determined by HPLC and the dissolution of gastrodine was studied with a specialized release-measuring apparatus made-self in 40 mL artificial saliva at the detection wavelength of 420 nm. Result The linear range of gastrodine was from 0. 042 to 0. 378 μg and the average recovery was 99.18% with a RSD of 2.40%.Approximately 90.0% of the gastrodine contained in Gastrodia elata chewing gums was released in about 8 min. Conclusion Gastrodia elata chewing gum is a fast-released preparations and suitable for lowering blood pressure and treating headaches.关键词
天麻咀嚼胶/释放度/天麻素/释放度测定仪Key words
Gastrodia elata chewing gum/release/gastrodine/release-measuring apparatus分类
医药卫生引用本文复制引用
周霞,谌介秀,万军..全天麻咀嚼胶体外释放度的测定[J].广东药学院学报,2014,(4):404-407,4.基金项目
中央高校基本科研业务费专项资金资助项目(2682013CX035) （2682013CX035）
