国际妇产科学杂志Issue(2):98-102,111,6.
子宫内膜异位症的三维模型研究进展
Progress in Three Dimensional Models of Endometriosis
摘要
Abstract
Endometriosis (EMs) is the presence of endometrial glandular and stromal cells outside of the uterine cavity , and is the most common disorder in reproductive women. Quality of life for these women is predictable to be negatively affected. For the poor understanding about the pathophysiology of endometriosis ,no current medical therapy has been demonstrated to be effective in eradicating the disease or in preventing it without unacceptable side effects. Concerning about the uncertainties about the pathophysiology of endometriosis ,the establishment of an appropriate human EMs model plays a pivotal role in the study of endometriosis. This review tends to sum up the establishment and development of the endometriosis three-dimensional models (3D models) and assesses the methods and materials,different potential and limitation regarding to endometriosis researches,with the aim of developing novel simulating models for the further study.关键词
子宫内膜异位症/体外研究/模型,动物/三维模型Key words
Endometriosis/In vitro/Models,animal/Three-dimensional models引用本文复制引用
梁莉莉,林毅豪,王宁宁..子宫内膜异位症的三维模型研究进展[J].国际妇产科学杂志,2014,(2):98-102,111,6.基金项目
国家自然科学基金(81170550,30672222);广东省自然科学基金(8151008901000124);广东省科技计划项目(2010B050700009,2007B080701011);广州市科技计划项目(2010Y-C011),广东省医学科学技术研究基金(A2009672);中山大学附属第一医院人才培养计划 ()