国际妇产科学杂志Issue(3)：213-217,5.
代谢组学方法在妊娠期糖尿病研究中的应用
The Application of Metabolomics for Gestational Diabetes Mellitus
摘要
Abstract
Gestational diabetes mellitus (GDM) easily lead to some complications,such as preeclampsia, polyhydramnios,macrosomia,and so on. The traditional diagnostic protocols for GDM mainly rely on detecting elevated glucose levels in blood,often late in the second trimester. Therefore the treatment time for the patients is not enough and the serious risk to maternal and child health raise. Metabolomics is an approach that investigates the metabolic responses of living systems to internal or external stimuli or genetic modification. The application of metabolomics to GDM research will help to interpret the pathogenesis of GDM. In addition,it can also provide the theoretical and experimental support for prevention and treatment of GDM as well as the prognosis of mothers and their infants. The characteristics of the common detection methods and the metabolomics studies of GDM were analyzed and compared in detail in this paper ,and the metabolomic studies in GDM was further reviewed.关键词
糖尿病,妊娠/羊水/血浆/尿/代谢组学Key words
Diabetes,gestational/Amniotic fluid/Plasma/Urine/Metabolomics引用本文复制引用
周玲,沈桂平,许晶晶,邓伶莉,董继扬(审校),黄秀敏(审校)..代谢组学方法在妊娠期糖尿病研究中的应用[J].国际妇产科学杂志,2014,(3):213-217,5.基金项目
国家自然科学基金（81201143，81371639）；中央高校基本科研业务费 （）
