国际妇产科学杂志Issue(3):229-231,235,4.
MicroRNA-375在妇科恶性肿瘤中的研究进展
Research Progress of MicroRNA-375 in Gynecological Malignant Tumors
摘要
Abstract
MicroRNA-375 is a highly conservative miRNA,which play important roles in suppressing proliferation, promoting apoptosis,suppressing invasion and metastasis by means of regulating the expression of genes. The research has revealed that miR-375 is remarkably down-regulated in many tumor cells and ontic tissues ,and is closely related in cancer development and progression. Recent years ,the research on miR-375 in cervical cancer and endometrial cancer is increasing , but the mechanism should be studied future. This article elaborates biological function of miR-375 and improvements of some studies in gynecological malignant tumors.关键词
微RNAs/肿瘤/宫颈肿瘤/子宫内膜肿瘤/细胞增殖/细胞凋亡Key words
MicroRNAs/Neoplasms/Uterine cervical neoplasms/Endometrial neoplasms/Cell proliferation/Apoptosis引用本文复制引用
张利利,郝敏,赵卫红..MicroRNA-375在妇科恶性肿瘤中的研究进展[J].国际妇产科学杂志,2014,(3):229-231,235,4.基金项目
山西省卫生厅科技攻关计划项目(20100108);山西省卫生厅青年项目 ()