摘要
Abstract
Objective To analyze the clinical features, laboratory and imaging characteristics of endocardial fibroelastosis ( EFE) in children, and to follow up treatment outcomes.Methods Retrospective study was conducted on 60 cases with EFE admitted in the second department of pediatrics in Taihe Hospital of Shiyan during the period of December 2000 to June 2011.Their clinical features, physical signs, laboratory and imaging characteristics were summarized and follow-up results were recorded.Results The main causes of the first visit of EFE children were pneumonia and heart failure (55%).Cough (75.0%), dyspnea (68.3%) and shortness of breath (83.3%) were major clinical symptoms.The main changes in electrocardiogram included left ventricular hypertrophy with strain (38.3%), left ventricular hypertrophy alone (15.0%), sinus tachycardia (30.0%) and ST-T changes (11.7%).Chest X-ray examination showed larger heart (100.0%) and cardiothoracic ratio>0.60 (38.3%).Echocardiography showed expanded left ventricular (100.00%), thickened left ventricular endocardium, echo enhancement ( 81.7%) , decreased left ventricular systolic function ( 100%) , and left ventricular ejection fraction (EF) less than 55%(100%).After treatment, 41 cases were improved (68.3%), 12 cases were discharged (20.0%) and 7 cases died (11.7%).Six cases were lost in follow-up.Of 47 cases with follow-up the disease aggravated in 4 cases (8.5%) and 1 case (2.1%) died of heart failure.Conclusion Echocardiography can detect the characteristic performance of EFE and long-term treatment can improve the prognosis of patients.关键词
心内膜弹力纤维增生症/临床表现/超声检查/预后Key words
endocardial fibroelastosis ( EFE)/clinical manifestation/ultrasonography/prognosis分类
医药卫生
