中国妇幼健康研究Issue(5)：811-813,3.DOI:10.3969/j.issn.1673-5293.2014.05.036
剖宫产围手术期短疗程使用抗生素的临床疗效
Clinical efficacy of short course of antibiotics on perioperative cesarean section
徐娜 1马锦琪 1任春霞 1吕祝武1
作者信息
- 1. 南京医科大学附属无锡市人民医院妇产科，江苏无锡214000
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of short course of antibiotics on perioperative cesarean section.Methods One hundred pregnant women undergoing selective cesarean section during the period of June 2012 to March 2014 were selected from obstetrics department of People’ s Hospital of Wuxi Affiliated Nanjing Medical University.They were divided into experimental group and control group with 50 cases in each according to random number.Cefotaxime sodium was given to the experimental group 30min before operation and maintenance dose was provided within 24h after clamping umbilical cord.The control group was provided with cefotaxime sodium 24h after clamping umbilical cord till hospital discharge.The effect of two antibiotics therapy was observed.Results In the control group the highest temperature after surgery was higher and time to remove fever was longer, and the differences were significant ( t value was 5.344 and 6.571, respectively, both P <0.05).Compared with the control group, the postoperative morbidity, surgical infection rate and incidence of endometritis were significantly lower in the experimental group (χ2 value was 4.332, 4.891 and 6.658, respectively, all P<0.05).There were no significant differences in gastrointestinal reactions and drug rash between two groups (χ2 value was 1.042 and 1.010, respectively, both P>0.05).The differences in postoperative leukocyte count and neutrophil count were not significant between two groups (t value was 2.552 and 1.132, respectively, both P>0.05).Conclusion Short course of antibiotics for perioperative cesarean section can significantly reduce body temperature and shorten fever time.Meanwhile, it can prevent postpartum infection effectively.关键词
剖宫产围手术期/短疗程/抗生素/疗效观察Key words
perioperative cesarean section/short course/antibiotics/curative efficacy observation分类
医药卫生引用本文复制引用
徐娜,马锦琪,任春霞,吕祝武..剖宫产围手术期短疗程使用抗生素的临床疗效[J].中国妇幼健康研究,2014,(5):811-813,3.
