川崎病患儿外周血 CD4＋CD25＋调节性 T细胞与 Th17细胞的变化OACSTPCD
Changes of CD4 +CD25 +regular T cells and Th17 cells in peripheral blood in children with Kawasaki disease
目的：探讨川崎病（ KD）患儿治疗前后外周血中CD4＋CD25＋调节性T细胞（ Treg）与Th17细胞比例的变化，以指导临床治疗及评估预后。方法选择KD患儿32例（ KD组）及健康幼儿28例（对照组）；抽取对照组幼儿和KD组患儿使用免疫球蛋白＋阿司匹林治疗前及治疗后热退3天时清晨空腹静脉血，采用ELISA双抗体夹心法检测血清中白细胞介素－15（ IL-15）、白细胞介素－17（IL-17）和白细胞介素－23（IL-23）水平；采用流式细胞术检测…查看全部>>
Objective To investigate the changes of CD4 +CD25 +regular T cells (Treg) and Th17 cells in peripheral blood in children with Kawasaki disease ( KD) before and after treatment , and to guide clinical treatment and evaluate prognosis .Methods A total of 32 KD children (KD group) and 28 healthy children (control group) were recruited.Morning peripheral vein bloods were collected from two groups before treated by immunoglobulin and aspirin and three days after …查看全部>>
卢红飞;林应荣;史澈;王乃飞
慈溪市第三人民医院儿科，浙江慈溪315324温岭市第一人民医院儿科，浙江温岭 317500慈溪市第三人民医院检验科，浙江慈溪 315324慈溪市第三人民医院儿科，浙江慈溪315324
医药卫生
川崎病儿童调节性T细胞Th17细胞
Kawasaki disease ( KD)childrenregular T cells ( Treg)Th17 cells
《中国妇幼健康研究》 2014 (6)
944-946,3
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