摘要
Abstract
Objective To analyze the risk factors of placental abruption (PA) in patients with preeclampsia (PE), so as to provide reference for the prevention of the disease .Methods From June 2010 to September 2013 268 cases with PE delivering in the maternity department of Jintai Hospital of Baoji City in Shaanxi Province were selected , including 48 cases combining PA in observation group and the other 220 cases not combining PA in control group .Clinical data of two groups were retrospectively analyzed , and the factors were analyzed with univariate analysis and multivariate Logistic regression analysis .Results Univariate analysis showed that the gestational age , fibrinogen (FIB) and serum albumin (ALB) in the observation group were significantly decreased than those in the control group (t value was 2.059, 3.591 and 8.200, respectively, all P<0.05), but diastolic pressure (DBP), blood urea nitrogen (BUN), creatinine (Cr) and 24h urine protein (24h UP) were significantly increased (t value was 2.652, 4.583, 6.852 and 3.632, respectively, all P<0.05).The childbirth history in the observation group was significantly lower than that in the control group (χ2 =8.731,P<0.05).Multivariate Logistic regression analysis showed that FIB , 24h UP, ALB, Cr and childbirth history were the independent risk factors for PE combining PA (OR value was 1.369, 1.198, 1.205, 1.283 and 1.231, respectively, all P<0.05).Conclusion The pathological mechanism of PA combining PE is complex, and it is related with FIB, 24h UP, ALB, Cr and childbirth history.The high-risk factors of PA should be found as early as possible in clinics , and effective measures should be taken to prevent the occurrence of PA .关键词
子痫前期/胎盘早剥/危险因素/单因素分析/Logistic回归分析Key words
preeclampsia ( PE)/placental abruption ( PA)/risk factors/univariate analysis/Logistic regression anlaysis分类
医药卫生
