中国妇幼健康研究Issue(6)：1057-1059,3.DOI:10.3969/j.issn.1673-5293.2014.06.051
稽留流产胚胎绒毛染色体异常的分析研究
Analysis of embryo villi chromosomal abnormality in missed abortion
任静 1张立军1
作者信息
- 1. 天津医科大学第二医院产科，天津 300211
- 折叠
摘要
Abstract
Objective To explore the relationship between missed abortion and embryo chromosomal abnormality .Methods Under aseptic conditions , embryo villi of 87 cases of missed abortion for the first time were collected , and long-term culture of villi chromosome specimens was prepared for 320-400 banding chromosome analysis .Results Totally 84 cases of villi chromosome were successfully prepared , with the successful rate of 96.6%.There were 45 cases with abnormal karyotype ( incidence of 53.6%) and 43 cases with abnormal chromosome number (incidence of 95.6%).The incidence of abnormal karyotype in patients older than and equal to 35 was 71.4%, and that in patients younger than 35 was 44.6%.The difference was significant (χ2 =5.385,P<0.05).Conclusion Abnormal chromosome number is one of the important causes of missed abortion .The incidence of chromosome number abnormality is especially high in patients older than and equal to 35.Villi chromosome analysis is an important means of diagnosing missed abortion pathogeny , and it can provide basis for guidance of eugenics in birth again .关键词
稽留流产/染色体异常/核型分析/优生优育Key words
missed abortion/chromosome abnormity/karyotype analysis/prepotency分类
医药卫生引用本文复制引用
任静,张立军..稽留流产胚胎绒毛染色体异常的分析研究[J].中国妇幼健康研究,2014,(6):1057-1059,3.
