医学分子生物学杂志Issue(6)：311-317,7.DOI:10.3870/j.issn.1672-8009.2014.06.001
体外受精-胚胎移植后生化妊娠的相关危险因素分析
Analysis of the Risk Factors for the Biochemical Pregnancy after In Vitro Fertilization and Embryo Transfer
摘要
Abstract
Objective To analyze various relevant factors that contribute to the development of the biochemical pregnancy or the clinical pregnancy after the IVF-ET in order to identify the factors related to the biochemical pregnancy. Methods Clinical data on 55 cycles of biochemical pregnan-cies and 100 cycles of clinical pregnancies were analyzed retrospectively. Step-wise logistic regression analysis was done to compare exposed influence factors between the two groups. Results Male age, primary or secondary infertility, use of gonadotropin-releasing hormone agonist in assisted reproduc-tion cycles, ratio of fertilization, basic antral follicle count (AFC) and spontaneous abortion were the significant influence factors for biochemical pregnancies ( P ﹤ 0. 05) . Furthermore, it was found that the basic AFC and the history of spontaneous abortion were the independent factors for bi-ochemical pregnancy. Conclusion The occurrence of biochemical pregnancy in the IVF-ET treat-ment is affected by the age, ovarian reserve, ovarian hyperstimulation program and history of spon-taneous abortion etc.关键词
体外受精-胚胎移植/生化妊娠/危险因素/Logistic 回归Key words
in vitro fertilization and embryo transfer/biochemical pregnancy/influential fac-tor/logistic regression分类
医药卫生引用本文复制引用
尹太郎,杨菁,夏曦,穆杨,李赛姣,解迪,张怡,丁锦丽,邹宇洁,徐望明..体外受精-胚胎移植后生化妊娠的相关危险因素分析[J].医学分子生物学杂志,2014,(6):311-317,7.基金项目
国家自然科学基金(No.81101971,81471508,81401276)This work was supported by a grant from the the National Natural Science Foundation of China (No.81101971,81471508,81401276) （No.81101971,81471508,81401276）
