医学分子生物学杂志Issue(2)：116-119,124,5.DOI:10.3870/j.issn.1672-8009.2015.02.011
调控因子在巨核细胞分化中的重要作用
Pivotal Role of Regulatory Factors in Megakaryocyte Differentiation
摘要
Abstract
Megakaryocytopoiesis is a process in which pluripotent hematopoietic stem cells give rise to megakaryocytes that undergo a series of proliferation and differentiation. It is a complicated and elaborate process controlled by related genes, which are turned on and off in proper order, and includes series of change in the cytoplasm and nuclei. Erythrocytes and megakaryocytes are origina-ted from the same precursor cells, and their differentiation mechanism remains elusive. Regulation on transcription factors is the key to study of megakaryocytopoiesis. This study reviews the advances in the study of related transcription factors during megakaryocytopoiesis.关键词
巨核细胞分化/转录因子/基因表达调控Key words
megakaryocyte differentiation/transcription factors/gene expression regulation分类
生物科学引用本文复制引用
隋娟,张高丽,仝温温,乔婷婷,李平法,于海川..调控因子在巨核细胞分化中的重要作用[J].医学分子生物学杂志,2015,(2):116-119,124,5.基金项目
国家自然科学基金(No.31301135),河南省教育厅科学技术研究重点项目(No.14B320015)This work was supported by grants from the National Nationnal Science Foundation of China (No.31301135), and the Science and Technology Research Program of the Education Department of Henan Province (No.14B3200015) （No.31301135）
