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微小RNA与宫颈癌

国际生殖健康/计划生育杂志Issue(4):297-300,4.
国际生殖健康/计划生育杂志Issue(4):297-300,4.

微小RNA与宫颈癌

MicroRNA and Cervical Cancer

摘要

Abstract

MicroRNA (miRNA), a class of endogenous small non-coding regulatory RNAs, regulate the expression of target genes by pairing with its 3′untranslated regions (3′UTR) to induce the inhibited translation or mRNA degression. Mature miRNA may interfere with multiple biological processes involved in tumorigenesis such as cell proliferation, cell cycle, apoptosis, angiogenesis, invasion and metastasis. Multiple studies showed that the aberrant expression of miRNA, as novel potential makers, could provide numerous promising merits in diagnostic, pathological and therapeutic targets in cervical cancer.

关键词

微RNAs/宫颈肿瘤//诊断/抗药性,肿瘤

Key words

MicroRNAs/Uterine cervical neoplasms/Carcinoma/Diagnosis/Drug resistance,neoplasm

引用本文复制引用

..微小RNA与宫颈癌[J].国际生殖健康/计划生育杂志,2014,(4):297-300,4.

国际生殖健康/计划生育杂志

OACSTPCD

1674-1889

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