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静息态脑功能成像在阿尔茨海默病早期诊断的研究进展

张友明 吕晓飞 李立

国际医学放射学杂志Issue(6):514-518,5.
国际医学放射学杂志Issue(6):514-518,5.DOI:10.3874/j.issn.1674-1897.2014.06.Z0601

静息态脑功能成像在阿尔茨海默病早期诊断的研究进展

Research progress of resting-state fMRI on the early diagnosis of Alzheimer’s disease

张友明 1吕晓飞 1李立1

作者信息

  • 1. 510060 广州,中山大学肿瘤防治中心影像与介入中心 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心
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摘要

Abstract

Alzheimer’s disease is a central nervous system degenerative disease characterized by progressive cognitive disorder and behavioral deficits. It is difficult to make an early diagnosis due to its insidious onset. Currently, researchers worldwide have been carrying on a lot of studies with various imaging techniques on the early diagnosis of Alzheimer’s disease. As a new imaging technique, resting-state fMRI emerged and developed rapidly in recent years. It has been widely used in the studies of Alzheimer’s disease due to its advantages such as various analysis methods, high practicality and patients’ better compliance. In this article, we reviewed the recent studies on the early diagnosis of Alzheimer’s disease by using resting-state fMRI, mainly on its analysis methods.

关键词

阿尔茨海默病/静息态功能磁共振成像/血氧水平依赖/功能连接/图论分析

Key words

Alzheimer’s disease/Resting-state fMRI/Blood oxygen level dependent/Functional connectivity/Graph theoretical analysis

引用本文复制引用

张友明,吕晓飞,李立..静息态脑功能成像在阿尔茨海默病早期诊断的研究进展[J].国际医学放射学杂志,2014,(6):514-518,5.

国际医学放射学杂志

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1674-1897

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