临床与病理杂志Issue(5):800-805,6.DOI:10.3978/j.issn.2095-6959.2015.05.021
2012~2014年鲍曼不动杆菌临床分布及耐药性分析
Clinical distribution and drug resistance of acinetobacter baumannii strains isolated during 2012 and 2014
张保荣 1徐婷 2梅亚宁 3陈友华 3文怡 3王珏 3顾兵3
作者信息
- 1. 宿迁市第一人民医院检验学部,江苏宿迁223800
- 2. 南京医科大学第一附属医院检验学部,南京210029
- 3. 南京医科大学第一附属医院检验学部,南京210029
- 折叠
摘要
Abstract
Objective:To investigate the clinical distribution and drug resistance of pathogens of acinetobacter baumannii (AB) strains isolated from the First Affiliated Hospital of Nanjing Medical University from 2012 to 2014. Methods:Automatic detection machine of VITEK-2 compact was used for identification of bacteria, as well as the drug susceptibility of the AB was performed by using disc agar diffusion (K-B method). All data were analyzed by WHONET5.6 or SPSS 19.0. Results:From 2012 to 2014, the separation rates of AB were 13.7%, 11.5%and 12.2%, respectively, higher than pseudomonas aeruginosa, lower only to Escherichia coli. hTe AB were mainly isolated from the department of intensive care unit (ICU, 44.6%), surgery (28.4%), and internal medicine (22.5%). A total of 79.2%isolates were from the respiratory tract specimens. hTe resistance rates to many kinds of antibiotics of AB strains were higher than 70.0%. hTe lower resistance rates of the AB to minocycline, amikacin, were 43.4%~55.8%and 50.1%~58.4%, respectively. hTere was a decrease in trend percentages during three years from 2012 to 2014. hTere were differences among the resistance rates of the AB isolated from different specimens and different departments. Conclusion:AB had been the most frequent non-fermentative pathogen causing clinical infection and the respiratory tract infection was dominant. hTough AB was highly resistance rate to clinical antibiotics, it had a downward trend. hTe use of antimicrobial drugs should continue to standardize.关键词
鲍曼不动杆菌/临床分布/耐药性/院内感染Key words
acinetobacter baumannii/clinical distribution/drug resistance/nosocomial infections引用本文复制引用
张保荣,徐婷,梅亚宁,陈友华,文怡,王珏,顾兵..2012~2014年鲍曼不动杆菌临床分布及耐药性分析[J].临床与病理杂志,2015,(5):800-805,6.