临床与病理杂志Issue(5)：840-845,6.DOI:10.3978/j.issn.2095-6959.2015.05.029
涎腺淋巴上皮癌的影像学与病理学特点分析
Radiological and pathological features of salivary glands lymphoepithelial carcinoma
摘要
Abstract
Objective:To determine the CT, MRI and pathological features of salivary gland lymphoepithelial carcinoma (LEC). Methods:hTe CT and MRI ifndings of 22 patients with histologically proved salivary gland LEC were retrospectively reviewed. Eighteen patients underwent plain and enhanced CT scans, and four patients underwent plain and enhanced MR scans. Results:Salivary gland LECs were located in parotid gland in 16 patients and submandibular gland in six patients. Tumor margin was well-deifned in six cases, and ill-deifned in 16 cases. On CT scans, density was homogeneous in 16 cases, and heterogeneous in two cases. Signal intensity was homogeneous in all four cases underwent MR scans. Hypo-signal intensity on T1WI and slight hyper-signal intensity were found in all four patients. Moderate enhancement was found in 12 patients while intense enhancement was found in remaining 10 patients. Invasion to adjacent structures were found in eight patients. Enlarged lymph nodes were found in 10 patients. Pathology show epithelial cells of tumors with lymphocytic interstitial infiltration and immunohistochemical median to highly expression of CK. Conclusion:Salivary gland LECs have some distinct imaging features that are characterized as homogeneous masses with moderate to intense enhancement but with less necrosis, and unilateral draining lymphadenopathy are common. hTe pathological changes with the characteristics of histology and immunohistochemistry detection, combined with the position imaging CT, MRI, rule out Metastasis of nasopharyngeal cancer can be diagnosed as primary salivary gland LEC.关键词
涎腺/淋巴上皮癌/体层摄影术,χ线计算机/磁共振成像/病理活检Key words
salivary gland/lymphoepithelial carcinoma/tomography/X-ray computed/magnetic resonance imaging/biopsy引用本文复制引用
杨通,张翔,段小慧,张芳,沈君..涎腺淋巴上皮癌的影像学与病理学特点分析[J].临床与病理杂志,2015,(5):840-845,6.基金项目
广东省科技计划项目(2013B021800222)。Tis work was supported by Guangdong Provincial Science and Technology Plan Projects (2013B021800222), P. R. China （2013B021800222）
