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雌激素受体GPR30心血管保护作用研究进展

马应旭(综述) 李向平(审校)

临床与病理杂志Issue(5):865-868,4.
临床与病理杂志Issue(5):865-868,4.DOI:10.3978/j.issn.2095-6959.2015.05.033

雌激素受体GPR30心血管保护作用研究进展

The cardiovascular protective effects of estrogen receptor GPR30

马应旭(综述) 1李向平(审校)2

作者信息

  • 1. 中南大学湘雅二医院心血管内科,长沙410011
  • 2. 中南大学湘雅医学院2012级八年制临床医学,长沙410013
  • 折叠

摘要

Abstract

hTe cardiovascular regulating and protective effects of G-protein coupled receptor 30 (GPR30) have become the hot topic since the study found that GPR30 could mediate rapid estrogen responses in the body. Researches showed that estrogen binding to GPR30 might affect endothelial cells, smooth muscle cells, and the renin-angiotensin system, resulting in vasodilation, a lowering of blood pressure, prevention of myocardial reperfusion injury, and improvement in blood lipid metabolism. However, the researches about GPR30 are limited in cell in vitro and animal experiments and the physiological and pathological effects in the body remain to be further studied.

关键词

G蛋白偶联受体30/雌激素/心血管保护作用

Key words

G-protein coupled receptor 30/estrogen/cardiovascular protective efect

引用本文复制引用

马应旭(综述),李向平(审校)..雌激素受体GPR30心血管保护作用研究进展[J].临床与病理杂志,2015,(5):865-868,4.

临床与病理杂志

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