临床与病理杂志Issue(6)：965-969,5.DOI:10.3978/j.issn.2095-6959.2015.06.019
恶性孤立性纤维性肿瘤4例临床病理分析并文献复习
Clinicopathologic analyses of malignant solitary fibrous tumor and review of the literature
邵云 1王海艳 1王晶晶 1许春伟 1吴永芳 1王怀涛 1张博 1李晓兵1
作者信息
- 1. 军事医学科学院附属医院理科，北京 100071
- 折叠
摘要
Abstract
Objective: To investigate the clinicopathologic characteristics, diagnosis and differential diagnosis, treatment and prognosis of malignant solitary fibrous tumor (MSFT).Methods: The clinical features, histological features and immunohistochemical features of the five cases diagnosed with MSFT were analyzed, the related literatures were reviewed.Results:Of the 4 patients with MSFT, two were males and two was female, aged 43~64 years. The neoplasms were located in intrathoracic cavity, mesentery of sigmoid colon, right shoulder and left foot. Histologically the tumor was composed of areas of altemating hypercellularity and hypocellularity. In some areas, hemangiopericytoma-like structure was present. hTe tumor cells were spindle to short-spindle shaped with marked nuclear atypia and increased mitotic activity. Focal hemorrhage and necrosis was present. Immunohistochemically, Vim, Bcl-2, CD99 and CD34 were positive, while CK and S-100 were negative in all the cases. Conclusion:MSFT is a rare mesenchymal tumor, and the diagnosis mainly relies on the pathological morphology and immunohistochemistry. To avoid misdiagnosis, it is important for us to be fully aware of this tumor.关键词
恶性孤立性纤维性肿瘤/临床病理特征/诊断/鉴别诊断Key words
malignant solitary fbrous tumor/clinicopathology/diagnosis/diferential diagnosis引用本文复制引用
邵云,王海艳,王晶晶,许春伟,吴永芳,王怀涛,张博,李晓兵..恶性孤立性纤维性肿瘤4例临床病理分析并文献复习[J].临床与病理杂志,2015,(6):965-969,5.
