临床与病理杂志Issue(6)：978-984,7.DOI:10.3978/j.issn.2095-6959.2015.06.021
膀胱嗜铬细胞瘤14例临床病理分析
A clinicopathological study of 14 cases of bladder pheochromocytoma
周良锐 1吴焕文 1钟定荣1
作者信息
- 1. 中国医学科学院，北京协和医院病理科，北京 100730
- 折叠
摘要
Abstract
Objective: To explore the clinicopathologic characteristics and histopathological diagnosis of bladder pheochromocytoma.Methods:A total of 14 cases of bladder pheochromocytoma were retrospectively retrieved from the surgical pathology ifles of Peking Union Medical College Hospital. hTe clinical and pathological ifndings were analyzed with a review of the literature.Results:Of the 14 patients with bladder pheochromocytoma, eight were males and six were females. hTe median age was 46.7 years (ranged from 14 to 63), and the median maximum diameter of the tumors was 2.5 cm (ranged from 0.2 to 8). Microscopic examination showed that the tumor cells were polygonal to spindle-shaped arranged into trabecular, solid or zellballen pattern in a rich vascular network. hTe tumor was typically not well circumscribed with inifltration of bladder wall. Immunohistochemical staining showed that CgA and Syn were positive for tumor cells, and S-100 was positive for the spindle cells around tumornests. AE1/AE3 was typically negative. Ki-67 index ranged from 1% to 10%. Nine cases received transurethral resection of bladder tumor, 4 cases of which had local recurrence. Five cases used bladder resection, 2 cases of which had local recurrence.Conclusion: Pheochromocytoma is a rare tumor of the bladder, and the pathological diagnosis is based on morphological and immunohistochemical characteristics. Local recurrence following tumor resection is common, while metastasis is rare.关键词
膀胱/嗜铬细胞瘤/临床病理分析Key words
bladder/pheochromocytoma/clinicopathological study引用本文复制引用
周良锐,吴焕文,钟定荣..膀胱嗜铬细胞瘤14例临床病理分析[J].临床与病理杂志,2015,(6):978-984,7.
