国际病理科学与临床杂志Issue(6)：1020-1025,6.DOI:10.3978/j.issn.2095-6959.2015.06.029
男性乳腺癌11例临床病理分析并文献复习
Clinicopathologic analyses of 11 male breast cancers and review of the literature
邵云 1王怀涛 1刘甲子 1王海艳 1王晶晶 1许春伟 1吴永芳 1张博 1李晓兵1
作者信息
- 1. 军事医学科学院附属医院理科，北京 100071
- 折叠
摘要
Abstract
Objective:To analyze the clinicopathologic characteristics and molecular subtype in male breast cancer (MBC). Methods:hTe clinical features, histological features and molecular subtype of the cases from January 2010 to December 2014 were analyzed, and the related literatures were reviewed.Results: Eleven patients were diagnosed with MBC, accounting for 0.92% of all the breast cancer in the same term. hTe median age was 61 (range from 38~80). Tumor is located in letf side in 7 cases, right side in 4 cases. Nine cases were diagnosed as invasive ductal carcinoma while the others were diagnosed as encapsulated papillary carcinoma with adjacent invasive carcinoma in one case. Four patients had lymphatic metastasis when the tumor was diagnosed. Immunohistochemically, ER was positive in all the cases, while PR was positive in 9 cases. In one case Her-2 was diagnosed as ++, +++ but FISH showed no amplification, and other cases Her-2 were diagnosed as 0 or 1+. Four cases were Luminal A type, while 7 were Luminal B type. Conclusion: MBC is a rare malignant neoplasm, and most patients are diagnosed older and at advanced clinical stage. It is important for both doctors and patients to be fully aware of this tumor for early diagnosis and treatment.关键词
男性乳腺癌/临床病理特征/免疫组织化学/分子亚型Key words
male breast cancer/clinicopathologic features/immunohistochemistry/molecular subtype引用本文复制引用
邵云,王怀涛,刘甲子,王海艳,王晶晶,许春伟,吴永芳,张博,李晓兵..男性乳腺癌11例临床病理分析并文献复习[J].国际病理科学与临床杂志,2015,(6):1020-1025,6.
