临床与病理杂志Issue(6):1117-1120,4.DOI:10.3978/j.issn.2095-6959.2015.06.048
13例前列腺导管腺癌临床病理分析
Clinicopathological analysis of 13 cases of prostate ductal adenocarcinom
付娟娟 1宋新兰 1胡小萍 1孙振柱1
作者信息
- 1. 新疆维吾尔自治区人民医院病理科,乌鲁木齐 830001
- 折叠
摘要
Abstract
Objective: To explore the clinicopathological features, diagnosis and differential diagnosis of prostate ductal adenocarcinoma (DAP).Methods: A total of 18 cases of DAP were reported by microscopy, immunohistochemistry, differentia diagnosis.Results: Most cases were accompanied by conventional prostate adenocarcinoma (61.35%), most of the prostate ductal adenocarcinoma cases were central type (76.92%). Histologically, tumors consist mostly of papillary, cribriform and tubular structures. Tumor cells showed tall columnar shape and nuclear atypia, abundant cytoplasm, have double color and nucleolus. Immunohistochemically results showed the tumor cell was positive for PSA and AR, P504s positive 12 cases, P63 and 34βE12positive in 1 case. hTe proliferation index of Ki-67 was 5%~80%.Conclusion:hTere are both clinicopathological and immunohistochemcial differences between the ductal carcinoma and conventional prostate adenocarcinoma. Prostate ductal adenocarcinoma should be distinguished from high grade prostate intraepithelial neoplasm, urothelial carcinoma involving the prostate and papillary adenoma of urethra.关键词
前列腺导管腺癌/临床病理/免疫组织化学/鉴别诊断Key words
prostate neoplsms ductal adenocarcinoma/clinicopathological/immunohistochemistry/diferential diagnosis引用本文复制引用
付娟娟,宋新兰,胡小萍,孙振柱..13例前列腺导管腺癌临床病理分析[J].临床与病理杂志,2015,(6):1117-1120,4.